Instruction Set Architecture

So base on different machine/computer architecture, there are following Instruction Set we need to learn. Thanks to John  von Neumann, I guess the types of machines is actually reduced by him.

-IA-64 (Itanium)
-MIPS
-IBM 700/7000 series
—-System/390
—-z/Architecture
-Power Architecture
—-POWER
—-PowerPC
-SPARC
-x86
—-IA-32 (i386, Pentium, Athlon)
—-x86-64 (64-bit superset of IA-32)